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Article

Requirements for comprehensive pharmacogenetic genotyping platforms.

Pharmacogenomics - 1 Jun 2016

Lauschke Volker M, Ingelman-Sundberg Magnus

Abstract excerpt

Recent research highlighted the large extent of rare variants in pharmacogenes and, on this basis, it was estimated that rare variants account for 30-40% of the functional variability in pharmacogenes. It has been proposed that comprehensive next-generation sequencing (NGS)-based sequencing of pharmacogenes could soon be a cost-effective methodology for clinical routine genotyping. Yet, multiple challenges on...

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PMID: 27248710
DOI: 10.2217/pgs-2016-0023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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