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Article

The Role of Next-Generation Sequencing in Pharmacogenetics and Pharmacogenomics.

Cold Spring Harbor perspectives in medicine - 1 Feb 2019

Schwarz Ute I, Gulilat Markus, Kim Richard B

Abstract excerpt

Inherited genetic variations in pharmacogenetic loci are widely acknowledged as important determinants of phenotypic differences in drug response, and may be actionable in the clinic. However, recent studies suggest that a considerable number of novel rare variants in pharmacogenes likely contribute to a still unexplained fraction of the observed interindividual variability. Next-generation sequencing (NGS)...

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Identifiers

PMID: 29844222
DOI: 10.1101/cshperspect.a033027
PMCID: PMC6360866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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