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Article

Variant discovery using next-generation sequencing and its future role in pharmacogenetics.

Pharmacogenomics - 1 May 2020

Russell Laura E, Schwarz Ute I

Abstract excerpt

Next-generation sequencing (NGS) has enabled the discovery of a multitude of novel and mostly rare variants in pharmacogenes that may alter a patient's therapeutic response to drugs. In addition to single nucleotide variants, structural variation affecting the number of copies of whole genes or parts of genes can be detected. While current guidelines concerning clinical implementation mostly act upon...

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PMID: 32338137
DOI: 10.2217/pgs-2019-0190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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