Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice.

Infection and immunity - 1 Mar 2013

Clare Simon, John Victoria, Walker Alan W, Hill Jennifer L, Abreu-Goodger Cei, Hale Christine, Goulding David, Lawley Trevor D, Mastroeni Pietro, Frankel Gadi, Enright Anton J, Vigorito Elena, Dougan Gordon

Abstract excerpt

MicroRNAs (miRNAs) are small noncoding molecules that control gene expression posttranscriptionally, with microRNA-155 (miR-155) one of the first to be implicated in immune regulation. Here, we show that miR-155-deficient mice are less able to eradicate a mucosal Citrobacter rodentium infection than wild-type C57BL/6 mice. miR-155-deficient mice exhibited prolonged colonization associated with a higher C....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis
Share to Enterobacteriaceae Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Mice, Knockout

Share to MicroRNAs

Share to Real-Time Polymerase Chain Reaction

Share to RNA, Ribosomal, 16S

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 23264052
DOI: 10.1128/IAI.00969-12
PMCID: PMC3584869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice.PMID 23264052Read ↗

Investigation of Host and Pathogen Contributions to Infectious Colitis Using the Citrobacter rodentium Mouse Model of Infection.Semantic proximity Read ↗

A novel C57BL/6 mouse model for the study of severe <i>Citrobacter rodentium</i> infectionSemantic proximity Read ↗

<i>Citrobacter rodentium</i> infection reveals preserved intestinal resilience in aged intestineSemantic proximity Read ↗

Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen <i>Citrobacter rodentium</i>Semantic proximity Read ↗

Central Role for B Lymphocytes and CD4 <sup>+</sup> T Cells in Immunity to Infection by the Attaching and Effacing Pathogen <i>Citrobacter rodentium</i>Semantic proximity Read ↗

Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistanceSemantic proximity Read ↗

Turicibacterales protect mice from severe <i>Citrobacter rodentium</i> infectionSemantic proximity Read ↗

MicroRNA-155 knockout mice are susceptible to Mycobacterium tuberculosis infection.Semantic proximity Read ↗

Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunitySemantic proximity Read ↗

Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice.Semantic proximity Read ↗

ATPIF1 deficiency Significantly Alleviates Citrobacter rodentium-Induced Ulcerative Colitis in MiceSemantic proximity Read ↗

Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.