Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unfolded Protein Response–Related Signature Associates With the Immune Microenvironment and Prognostic Prediction in Osteosarcoma

8 Jun 2022

Abstract excerpt

Background: Osteosarcoma is a highly malignant bone tumor commonly occurring in adolescents with a poor 5-year survival rate. The unfolded protein response (UPR) can alleviate the accumulation of misfolded proteins to maintain homeostasis under endoplasmic reticulum stress. The UPR is linked to the occurrence, progression, and drug resistance of tumors. However, the function of UPR-related genes (UPRRGs) in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35754801
DOI: 10.3389/fgene.2022.911346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unfolded Protein Response–Related Signature Associates With the Immune Microenvironment and Prognostic Prediction in OsteosarcomaPMID 35754801Read ↗

Prediction of endoplasmic reticulum stress-related features and indication of immune microenvironment for the prognosis of osteosarcomaSemantic proximity Read ↗

Integrative Analysis of Necroptosis-Related Signature for Predicting the Prognosis of OsteosarcomaSemantic proximity Read ↗

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for OsteosarcomaSemantic proximity Read ↗

Molecular characterization of immunogenic cell death indicates prognosis and tumor microenvironment infiltration in osteosarcomaSemantic proximity Read ↗

Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcomaSemantic proximity Read ↗

Development of a novel immune-related genes prognostic signature for osteosarcomaSemantic proximity Read ↗

Expression of Lipid-Metabolism Genes Is Correlated With Immune Microenvironment and Predicts Prognosis in OsteosarcomaSemantic proximity Read ↗

Ferroptosis‐related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcomaSemantic proximity Read ↗

A Five-Immune-Related lncRNA Signature Predicts Survival of Patients With OsteosarcomaSemantic proximity Read ↗

Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis predictionSemantic proximity Read ↗

Comprehensive analysis of prognostic tumor microenvironment-related genes in osteosarcoma patientsSemantic proximity Read ↗

Identification and characterization of aging/senescence-induced genes in osteosarcoma and predicting clinical prognosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.