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Article

Interaction of TLR-IFN and HLA polymorphisms on susceptibility of chronic HBV infection in Southwest Han Chinese.

Liver international : official journal of the International Association for the Study of the Liver - 1 Aug 2015

He Dengming, Tao Shiqi, Guo Shimin, Li Maoshi, Wu Junqiu, Huang Hongfei, Guo Xinwu, Yan Guohua, Zhu Peng, Wang Yuming

Abstract excerpt

BACKGROUND & AIMS: The toll-like receptor-interferon (TLR-IFN) signalling pathway plays a crucial role in HBV infection. Human leucocyte antigen (HLA) polymorphisms are associated with chronic HBV infection by genome wide association study (GWAS). We aimed to explore interaction between TLR-IFN and HLA gene polymorphisms in susceptibility of chronic HBV infection. METHODS: In the Chinese Southwest Han population,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25469587
DOI: 10.1111/liv.12756
PMCID: PMC6680266

Genes

IFNGR1
IFNGR2
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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