Article
BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.
Atherosclerosis - 1 Aug 2016
van Dam Andrea D, Bekkering Siroon, Crasborn Malou, van Beek Lianne, van den Berg Susan M, Vrieling Frank, Joosten Simone A, van Harmelen Vanessa, de Winther Menno P J, Lütjohann Dieter, Lutgens Esther, Boon Mariëtte R, Riksen Niels P, Rensen Patrick C N, Berbée Jimmy F P
Abstract excerpt
BACKGROUND AND AIMS: Bacille-Calmette-Guérin (BCG), prepared from attenuated live Mycobacterium bovis, modulates atherosclerosis development as currently explained by immunomodulatory mechanisms. However, whether BCG is pro- or anti-atherogenic remains inconclusive as the effect of BCG on cholesterol metabolism, the main driver of atherosclerosis development, has remained underexposed in previous studies....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.