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Article

Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas.

Oncotarget - 21 Jun 2016

Ghazzaui Nour, Saintamand Alexis, Issaoui Hussein, Saad Faten, Denizot Yves

Abstract excerpt

Functional B-cells are essential for the formation of oil granulomas. The IgH 3' regulatory region (3'RR) activates important check-points during B-cell maturation. We investigated if 3'RR-deficient B-cells remain efficient to develop oil granulomas in response to pristine. B-cells expressing an IgH 3'RR-deficient allele were similarly recruited to wild type allele expressing B-cells in the granuloma. No...

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Identifiers

PMID: 27231852
DOI: 10.18632/oncotarget.9588
PMCID: PMC5122425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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