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Article

FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2016

Ahn Soomin, Lee Jeeyun, Hong Mineui, Kim Seung Tae, Park Se Hoon, Choi Min Gew, Lee Jun-Ho, Sohn Tae Sung, Bae Jae Moon, Kim Sung, Jung Sin-Ho, Kang Won Ki, Kim Kyoung-Mee

Abstract excerpt

FGFR2 gene amplification, and resulting FGFR2 protein overexpression, is rare in gastric cancer patients, and development of an accurate and widely available method for mass screening to identify patients who may respond to treatment with fibroblast growth factor receptor (FGFR) inhibitors is important. We first screened 312 gastric cancer patients with known copy number variations by FGFR2b immunohistochemistry...

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Identifiers

PMID: 27230412
DOI: 10.1038/modpathol.2016.96

Genes

FGFR2
FPR2

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