Association of genetic risk score and chronic kidney disease in a Japanese population.

doi:10.1111/nep.13479

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Article

Association of genetic risk score and chronic kidney disease in a Japanese population.

Nephrology (Carlton, Vic.) - 1 Jun 2019

Fujii Ryosuke, Hishida Asahi, Nakatochi Masahiro, Furusyo Norihiro, Murata Masayuki, Tanaka Keitaro, Shimanoe Chisato, Suzuki Sadao, Watanabe Miki, Kuriyama Nagato, Koyama Teruhide, Takezaki Toshiro, Shimoshikiryo Ippei, Arisawa Kokichi, Katsuura-Kamano Sakurako, Takashima Naoyuki, Turin Tanvir C, Kuriki Kiyonori, Endoh Kaori, Mikami Haruo, Nakamura Yohko, Oze Isao, Ito Hidemi, Kubo Michiaki, Momozawa Yukihide, Kondo Takaaki, Naito Mariko, Wakai Kenji

Abstract excerpt

Chronic kidney disease (CKD) is a public health problem worldwide including Japan. Recent genome-wide association studies have discovered CKD susceptibility variants. We developed a genetic risk score (GRS) based on CKD-associated variants and assessed a possibility that the GRS can improve the discrimination capability for the prevalence of CKD in a Japanese population. The present study consists of 11 283...

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PMID: 30146708
DOI: 10.1111/nep.13479

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