Article
TH17 Cells in STAT3 Related Hyper-IgE Syndrome.
Indian journal of pediatrics - 1 Oct 2016
Sharma Sudha, Saikia Biman, Goel Shubham, Rawat Amit, Minz Ranjana W, Suri Deepti, Chhabra Seema, Singh Surjit
Abstract excerpt
OBJECTIVES: To assess the utility of T helper17 (TH17) cell enumeration vis-à-vis National Institutes of Health (NIH) scoring in Hyper IgE syndrome (HIES). METHODS: Clinical phenotypes of Hyper IgE syndrome patients with and without STAT3 mutation were analysed and correlated with absolute eosinophil count, serum IgE levels and TH17 cell numbers in 19 patients with clinically suspected HIES and compared with...
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