Article
Expression quantitative trait loci in long non-coding RNA PAX8-AS1 are associated with decreased risk of cervical cancer.
Molecular genetics and genomics : MGG - 1 Aug 2016
Han Jing, Zhou Wen, Jia Meiqun, Wen Juan, Jiang Jie, Shi Jufang, Zhang Kai, Ma Hongxia, Liu Jibin, Ren Jiansong, Dai Min, Hu Zhibin, Hang Dong, Li Ni, Shen Hongbing
Abstract excerpt
Paired box 8 (PAX8) is a crucial nephric-lineage transcription factor, and its aberrant expression has been detected in various types of cancer including Müllerian carcinomas. PAX8 antisense RNA 1 (PAX8-AS1), a potential regulator of PAX8, contains specific single nucleotide polymorphisms (SNPs) that may represent expression quantitative trait loci (eQTLs) for PAX8. In this study, we hypothesized that these eQTLs...
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