Article
Phenotypic Diversity Using Bimodal and Unimodal Expression of Stress Response Proteins.
Biophysical journal - 24 May 2016
Garcia-Bernardo Javier, Dunlop Mary J
Abstract excerpt
Populations of cells need to express proteins to survive the sudden appearance of stressors. However, these mechanisms may be taxing. Populations can introduce diversity, allowing individual cells to stochastically switch between fast-growing and stress-tolerant states. One way to achieve this is to use genetic networks coupled with noise to generate bimodal distributions with two distinct subpopulations, each...
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