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Article

Coagulation factor XIII deficiency. Diagnosis, prevalence and management of inherited and acquired forms.

Hamostaseologie - 1 Jan 2014

Biswas A, Ivaskevicius V, Thomas A, Oldenburg J

Abstract excerpt

The plasma circulating zymogenic coagulation factor XIII (FXIII) is a protransglutaminase, which upon activation by thrombin and calcium cross-links preformed fibrin clots/fibrinolytic inhibitors making them mechanically stable and less susceptible to fibrinolysis. The zymogenic plasma FXIII molecule is a heterotetramer composed of two catalytic FXIII-A and two protective FXIII-B subunits. Factor XIII deficiency...

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Identifiers

PMID: 24503678
DOI: 10.5482/HAMO-13-08-0046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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