Article
Investigating causality in the association between 25(OH)D and schizophrenia.
Scientific reports - 24 May 2016
Taylor Amy E, Burgess Stephen, Ware Jennifer J, Gage Suzanne H, Richards J Brent, Davey Smith George, Munafò Marcus R
Abstract excerpt
Vitamin D deficiency is associated with increased risk of schizophrenia. However, it is not known whether this association is causal or what the direction of causality is. We performed two sample bidirectional Mendelian randomization analysis using single nucleotide polymorphisms (SNPs) robustly associated with serum 25(OH)D to investigate the causal effect of 25(OH)D on risk of schizophrenia, and SNPs robustly...
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