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Article

Empirical analysis of RNA robustness and evolution using high-throughput sequencing of ribozyme reactions.

Methods (San Diego, Calif.) - 15 Aug 2016

Hayden Eric J

Abstract excerpt

RNA molecules provide a realistic but tractable model of a genotype to phenotype relationship. This relationship has been extensively investigated computationally using secondary structure prediction algorithms. Enzymatic RNA molecules, or ribozymes, offer access to genotypic and phenotypic information in the laboratory. Advancements in high-throughput sequencing technologies have enabled the analysis of...

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Identifiers

PMID: 27215494
DOI: 10.1016/j.ymeth.2016.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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