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Article

Long-term Variability in Glycemic Control Is Associated With White Matter Hyperintensities in APOE4 Genotype Carriers With Type 2 Diabetes.

Diabetes care - 1 Jun 2016

Livny Abigail, Ravona-Springer Ramit, Heymann Anthony, Priess Rachel, Kushnir Tammar, Tsarfaty Galia, Rabinov Leeron, Moran Reut, Hoffman Hadass, Cooper Itzik, Greenbaum Lior, Silverman Jeremy, Sano Mary, Johnson Sterling C, Bendlin Barbara B, Schnaider Beeri Michal

Abstract excerpt

OBJECTIVE: We assessed whether the apolipoprotein ε4 (APOE4) genotype affects the relationship of variability in long-term glycemic control (measured by HbA1c SD of multiple measurements) with white matter hyperintensities (WMHs) in elderly patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: WMH volume was generated from structural T1 and fluid-attenuated inversion recovery MRI in each subject. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27208321
DOI: 10.2337/dc15-2331
PMCID: PMC5317241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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