Article
Type 1 diabetes genetic risk score discriminates between monogenic and Type 1 diabetes in children diagnosed at the age of <5 years in the Iranian population.
Diabetic medicine : a journal of the British Diabetic Association - 1 Dec 2019
Yaghootkar H, Abbasi F, Ghaemi N, Rabbani A, Wakeling M N, Eshraghi P, Enayati S, Vakili S, Heidari S, Patel K, Sayarifard F, Borhan-Dayani S, McDonald T J, Ellard S, Hattersley A T, Amoli M M, Vakili R, Colclough K
Abstract excerpt
AIM: To examine the extent to which discriminatory testing using antibodies and Type 1 diabetes genetic risk score, validated in European populations, is applicable in a non-European population. METHODS: We recruited 127 unrelated children with diabetes diagnosed between 9 months and 5 years from two centres in Iran. All children underwent targeted next-generation sequencing of 35 monogenic diabetes genes. We...
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