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Article

miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers.

Cancer research - 15 Jul 2016

Langsch Stephanie, Baumgartner Ulrich, Haemmig Stefan, Schlup Cornelia, Schäfer Stephan C, Berezowska Sabina, Rieger Gregor, Dorn Patrick, Tschan Mario P, Vassella Erik

Abstract excerpt

A global understanding of miRNA function in EGFR signaling pathways may provide insights into improving the management of KRAS-mutant lung cancers, which remain relatively recalcitrant to treatment. To identify miRNAs implicated in EGFR signaling, we transduced bronchial epithelial BEAS-2B cells with retroviral vectors expressing KRAS(G12V) and monitored miRNA expression patterns by microarray analysis. Through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27199349
DOI: 10.1158/0008-5472.CAN-15-2580

Genes

KRAS
EGFR
TNFAIP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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