Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity

19 May 2016

Abstract excerpt

Immunoglobulin heavy chain ( IGH ) and light chain gene sequences of 27 patients with primary cold agglutinin disease (CAD) were studied to find features explaining the heterogeneity of clinical presentation and disease activity. CAD is a hemolytic anemia mediated by monoclonal IgM anti-I

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Chronic Lymphocytic Leukemia Research
Share to Immunodeficiency and Autoimmune Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27198717
DOI: 10.3324/haematol.2016.146126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activityPMID 27198717Read ↗

The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levelsSemantic proximity Read ↗

A case of cold agglutinin syndrome associated with chronic lymphocytic leukaemia harbouring mutations in CARD11 and KMT2D.Semantic proximity Read ↗

Cold agglutinin–associated B-cell lymphoproliferative disease shows highly recurrent gains of chromosome 3 and 12 or 18Semantic proximity Read ↗

Primary cold agglutinin-associated lymphoproliferative disease: a B-cell lymphoma of the bone marrow distinct from lymphoplasmacytic lymphomaSemantic proximity Read ↗

Cold Agglutinin-Mediated Autoimmune Hemolytic AnemiaSemantic proximity Read ↗

Chronic ataxic neuropathy with cold agglutinins: atypical phenotype and response to anti-CD20 antibodies.Semantic proximity Read ↗

Chronic lymphocytic leukemia preceded by cold agglutinin disease: intraclonal immunoglobulin light-chain diversity inVH4-34 expressing single leukemic B cellsSemantic proximity Read ↗

Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease: CARDINAL study 1-year interim follow-up resultsSemantic proximity Read ↗

Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.Semantic proximity Read ↗

VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificitiesSemantic proximity Read ↗

Association of a common dog leucocyte antigen class II haplotype with canine primary immune-mediated haemolytic anaemia.Semantic proximity Read ↗

Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.