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Article

Role of Plasmodium vivax Duffy-binding protein 1 in invasion of Duffy-null Africans.

Proceedings of the National Academy of Sciences of the United States of America - 31 May 2016

Gunalan Karthigayan, Lo Eugenia, Hostetler Jessica B, Yewhalaw Delenasaw, Mu Jianbing, Neafsey Daniel E, Yan Guiyun, Miller Louis H

Abstract excerpt

The ability of the malaria parasite Plasmodium vivax to invade erythrocytes is dependent on the expression of the Duffy blood group antigen on erythrocytes. Consequently, Africans who are null for the Duffy antigen are not susceptible to P. vivax infections. Recently, P. vivax infections in Duffy-null Africans have been documented, raising the possibility that P. vivax, a virulent pathogen in other parts of the...

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Identifiers

PMID: 27190089
DOI: 10.1073/pnas.1606113113
PMCID: PMC4896682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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