Article
Whole genome nucleosome sequencing identifies novel types of forensic markers in degraded DNA samples.
Scientific reports - 18 May 2016
Dong Chun-Nan, Yang Ya-Dong, Li Shu-Jin, Yang Ya-Ran, Zhang Xiao-Jing, Fang Xiang-Dong, Yan Jiang-Wei, Cong Bin
Abstract excerpt
In the case of mass disasters, missing persons and forensic caseworks, highly degraded biological samples are often encountered. It can be a challenge to analyze and interpret the DNA profiles from these samples. Here we provide a new strategy to solve the problem by taking advantage of the intrinsic structural properties of DNA. We have assessed the in vivo positions of more than 35 million putative nucleosome...
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