Article
A new SNP assay for identification of highly degraded human DNA.
Forensic science international. Genetics - 1 May 2012
Freire-Aradas A, Fondevila M, Kriegel A-K, Phillips C, Gill P, Prieto L, Schneider P M, Carracedo A, Lareu M V
Abstract excerpt
There is growing evidence that the histone-DNA complexes found in nucleosomes offer protection from DNA degradation processes, including apoptotic events in addition to bacterial and environmental degradation. We sought to locate human nucleosome regions and build a catalogue of SNPs sited near the middle of these genomic segments that could be combined into a single PCR multiplex specifically for use with...
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