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Mammalian African trypanosome VSG coat enhances tsetse’s vector competence

16 May 2016

Abstract excerpt

Tsetse flies are biological vectors of African trypanosomes, the protozoan parasites responsible for causing human and animal trypanosomiases across sub-Saharan Africa. Currently, no vaccines are available for disease prevention due to antigenic variation of the Variant Surface Glycoproteins (VSG) that coat parasites while they reside within mammalian hosts. As a result, interference with parasite development in...

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PMID: 27185908
DOI: 10.1073/pnas.1600304113

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