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Article

Gender differences in CNV burden do not confound schizophrenia CNV associations.

Scientific reports - 17 May 2016

Han Jun, Walters James T R, Kirov George, Pocklington Andrew, Escott-Price Valentina, Owen Michael J, Holmans Peter, O'Donovan Michael C, Rees Elliott

Abstract excerpt

Compared with the general population, an excess of rare copy number variants (CNVs) has been identified in people with schizophrenia. Females with neurodevelopmental disorders and in the general population have been reported to carry more large, rare CNVs than males. Given that many schizophrenia datasets do not have equal gender ratios in cases and controls, sex differences in CNV burden might have impacted on...

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Identifiers

PMID: 27185616
DOI: 10.1038/srep25986
PMCID: PMC4869015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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