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Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging

19 Feb 2021

Abstract excerpt

During aging, the skin undergoes changes in architecture and composition. Skin aging phenotypes occur due to accumulated changes in the genome/epigenome, cytokine/cell adhesion, cell distribution/extracellular matrix (ECM), etc. Here we review data suggesting that tissue mechanics also plays a role in skin aging. While mouse and human skin share some similarities, their skin architectures differ in some respects....

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PMID: 33681217
DOI: 10.3389/fcell.2021.635340

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