Article

Chikungunya and Mayaro Viruses Induce Chronic Skeletal Muscle Atrophy Triggered by Pro-inflammatory and Oxidative Response

2024-06-21

Abstract excerpt

Chikungunya (CHIKV) and Mayaro (MAYV) viruses are arthritogenic alphaviruses that promote an incapacitating and long-lasting inflammatory muscle-articular disease. Despite studies pointing out the importance of skeletal muscle (SkM) in viral pathogenesis, the long-term consequences on its physiology after acute injury and the mechanism of persistence of symptoms are still poorly understood. Combining molecular, mo...

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Literature Corpus work: 65caad88-1d8b-5a61-996a-0c50381a5dfb
DOI: 10.20944/preprints202406.1490.v1

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