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Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts

13 May 2016

Abstract excerpt

Genome editing on human pluripotent stem cells (hPSCs) together with the development of protocols for organ decellularization opens the door to the generation of autologous bioartificial hearts. Here we sought to generate for the first time a fluorescent reporter human embryonic stem cell (hESC) line by means of Transcription activator-like effector nucleases (TALENs) to efficiently produce cardiomyocyte-like...

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PMID: 27179434
DOI: 10.1016/j.biomaterials.2016.04.003

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