Article
Association of the Genetic Polymorphisms RRM1 -756T>C and -269C>A With Cervical Neoplasia.
Biological research for nursing - 1 Oct 2016
Chang Ching-Wen, Yang Shun-Fa, Wang Po-Hui, Chang Hsiu-Ju, Liu Wen-Chi, Tsai Hsiu-Ting
Abstract excerpt
Cervical neoplasia is one of the most prevalent malignant neoplasms worldwide. Ribonucleotide reductase 1 (RRM1) is thought to play an essential role in modulating the development and progression of cervical neoplasia. Two novel genetic polymorphisms, RRM1 -756T>C and -269 C>A, are significantly correlated with RRM1 expression. Some epidemiological studies have demonstrated that genetic variants play a crucial...
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