Article
TLR9 gene polymorphism -1486T/C (rs187084) is associated with uterine cervical neoplasm in Mexican female population.
Journal of cancer research and clinical oncology - 1 Dec 2017
Martínez-Campos Cecilia, Bahena-Román Margarita, Torres-Poveda Kirvis, Burguete-García Ana I, Madrid-Marina Vicente
Abstract excerpt
PURPOSE: The aim of this work was to evaluate the association of single nucleotide polymorphisms in TLR9 (-1486 T/C [rs187084], -1237T/C [rs5743836] and G2848A [rs352140]) with HPV infection, squamous intraepithelial lesions, and uterine cervical neoplasm in a Mexican population. Additionally, the peripheral expression of TLR9 was evaluated to evaluate the differences in the TLR9 expression associated with every...
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