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Article

Association between periodontitis and common variants in the promoter of the interleukin-6 gene.

Cytokine - 1 Jan 2009

Nibali L, D'Aiuto F, Donos N, Griffiths G S, Parkar M, Tonetti M S, Humphries S E, Brett P M

Abstract excerpt

We recently reported an association between interleukin-6 (IL6) polymorphisms (SNPs) and haplotypes and aggressive periodontitis (AgP). The aim of this study was to investigate this association in a larger cohort of subjects, affected by either aggressive or chronic periodontitis. Five IL6 SNPs were analyzed in 765 subjects (167 generalized aggressive periodontitis, 57 localized aggressive, 310 chronic...

Topics

Adult
Aged
Alleles
Female
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Interleukin-6
Linkage Disequilibrium
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Periodontitis

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Source

Identifiers

PMID: 19084430
DOI: 10.1016/j.cyto.2008.10.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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