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Article

Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype.

PloS one - 1 Jan 2016

Munthe Sune, Petterson Stine Asferg, Dahlrot Rikke Hedegaard, Poulsen Frantz Rom, Hansen Steinbjørn, Kristensen Bjarne Winther

Abstract excerpt

Gliomas are highly infiltrative tumors incurable with surgery. Although surgery removes the bulk tumor, tumor cells in the periphery are left behind resulting in tumor relapses. The aim of the present study was to characterize the phenotype of tumor cells in the periphery focusing on tumor stemness, proliferation and chemo-resistance. This was investigated in situ in patient glioma tissue as well as in orthotopic...

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PMID: 27171431
DOI: 10.1371/journal.pone.0155106
PMCID: PMC4865242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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