Article
Addressing resistance to antibiotics in systematic reviews of antibiotic interventions.
The Journal of antimicrobial chemotherapy - 1 Sept 2016
Leibovici Leonard, Paul Mical, Garner Paul, Sinclair David J, Afshari Arash, Pace Nathan Leon, Cullum Nicky, Williams Hywel C, Smyth Alan, Skoetz Nicole, Del Mar Chris, Schilder Anne G M, Yahav Dafna, Tovey David
Abstract excerpt
Antibiotics are among the most important interventions in healthcare. Resistance of bacteria to antibiotics threatens the effectiveness of treatment. Systematic reviews of antibiotic treatments often do not address resistance to antibiotics even when data are available in the original studies. This omission creates a skewed view, which emphasizes short-term efficacy and ignores the long-term consequences to the...
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