Article
Assessment of pharmacogenetic tests: presenting measures of clinical validity and potential population impact in association studies.
The pharmacogenomics journal - 1 Jul 2017
Tonk E C M, Gurwitz D, Maitland-van der Zee A-H, Janssens A C J W
Abstract excerpt
The progressing discovery of genetic variants associated with drug-related adverse events has raised expectations for pharmacogenetic tests to improve drug efficacy and safety. To further the use of pharmacogenetics in health care, tests with sufficient potential to improve efficacy and safety, as reflected by good clinical validity and population impact, need to be identified. The potential benefit of...
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