Article
Pharmacogenetics to predict drug-related adverse events.
Toxicologic pathology - 1 Jan 2000
Hosford David A, Lai Eric H, Riley John H, Xu Chun-Fang, Danoff Theodore M, Roses Allen D
Abstract excerpt
Identification of reliable markers to predict drug-related adverse events (DRAEs) is an important goal of the pharmaceutical industry and others within the healthcare community. We have used genetic polymorphisms, including the most frequent source of variation (single nucleotide polymorphisms, SNPs) in the human genome, in pharmacogenetic approaches designed to predict DRAEs. Three studies exemplify the...
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