Article
Conserved mechanism of Oxa1 insertion into the mitochondrial inner membrane.
Journal of molecular biology - 2 Dec 2005
Reif Sebastian, Randelj Olga, Domanska Grazyna, Dian Elke A, Krimmer Thomas, Motz Christian, Rassow Joachim
Abstract excerpt
Oxa1 is the mitochondrial representative of a family of related proteins that mediate the insertion of substrate proteins into the membranes of bacteria, chloroplasts, and mitochondria. Several studies have demonstrated that the bacterial homologue YidC participates both in the direct uptake of proteins from the bacterial cytosol, and in the uptake of nascent proteins from the Sec translocase. Studies on the...
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