Article
High-throughput cis-regulatory element discovery in the vector mosquito Aedes aegypti.
BMC genomics - 10 May 2016
Behura Susanta K, Sarro Joseph, Li Ping, Mysore Keshava, Severson David W, Emrich Scott J, Duman-Scheel Molly
Abstract excerpt
BACKGROUND: Despite substantial progress in mosquito genomic and genetic research, few cis-regulatory elements (CREs), DNA sequences that control gene expression, have been identified in mosquitoes or other non-model insects. Formaldehyde-assisted isolation of regulatory elements paired with DNA sequencing, FAIRE-seq, is emerging as a powerful new high-throughput tool for global CRE discovery. FAIRE results in...
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