Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deep sequencing reveals increased DNA methylation in chronic rat epilepsy

4 Sept 2013

Abstract excerpt

Epilepsy is a frequent neurological disorder, although onset and progression of seizures remain difficult to predict in affected patients, irrespective of their epileptogenic condition. Previous studies in animal models as well as human epileptic brain tissue revealed a remarkably diverse pattern of gene expression implicating epigenetic changes to contribute to disease progression. Here we mapped for the first...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet and metabolism studies
Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24005891
DOI: 10.1007/s00401-013-1168-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deep sequencing reveals increased DNA methylation in chronic rat epilepsyPMID 24005891Read ↗

Genome‐wide decrease in DNA methylation in adults with epilepsy treated with modified ketogenic diet: A prospective studySemantic proximity Read ↗

The Epigenetics of Epilepsy and Its ProgressionSemantic proximity Read ↗

Alterations in DNA 5-hydroxymethylation patterns in the hippocampus of an experimental model of chronic epilepsySemantic proximity Read ↗

Alterations in DNA 5-hydroxymethylation Patterns in the Hippocampus of an Experimental Model of Refractory EpilepsySemantic proximity Read ↗

The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?Semantic proximity Read ↗

Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis.Semantic proximity Read ↗

METHYLATION BIOMARKERS ASSOCIATED WITH DRUG-RESISTANT EPILEPSYSemantic proximity Read ↗

Etiology matters – Genomic DNA Methylation Patterns in Three Rat Models of Acquired EpilepsySemantic proximity Read ↗

Sarcosine Remodels DNA Methylation-Linked Transcriptional Networks During Epileptogenesis in the Rat Kindling ModelSemantic proximity Read ↗

The methylation hypothesis of pharmacoresistance in epilepsySemantic proximity Read ↗

H3K27 trimethylation maintains baseline network excitability in epilepsySemantic proximity Read ↗

Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.