Article
Associations between markers of colorectal cancer stem cells, mutation, microRNA and the clinical features of ulcerative colitis.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Jun 2016
Yang L, Levi E, Du J H, Zhou H H, Miller R, Majumdar A P N
Abstract excerpt
AIM: Several factors have been implicated in the pathogenesis of colorectal cancer (CRC) associated with ulcerative colitis (UC). We investigated markers of cancer cell pluripotency, including CD44 and CD166, microRNA-21 (miR-21) and microRNA-215 (miR-215), and APC, K-ras and DCC mutations in biopsy specimens from patients with UC to evaluate any correlations with clinical risk factors. METHOD: We observed 18...
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