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An Overview of Molecular Profiles in Ulcerative Colitis–Related Cancer

25 Jun 2018

Abstract excerpt

Ulcerative colitis (UC) is an independent risk factor of colorectal cancer (CRC). Both genetic and epigentic events induce a unique molecular profile during the development from UC to UC-related CRC (UCRC). These molecular changes play varied roles in DNA repair, immune response, cell metabolism, and interaction with the microbiota during the carcinogenesis process. This review will systmatically discuss the...

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Cancer-related molecular mechanisms research
Helicobacter pylori-related gastroenterology studies
Inflammatory Bowel Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29945208
DOI: 10.1093/ibd/izy221

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