Article
Conversion of adipogenic to osteogenic phenotype using crystalline porous biomatrices of marine origin.
Tissue engineering - 1 Jan 2006
Birk Ruth Z, Abramovitch-Gottlib Liat, Margalit Iris, Aviv Moran, Forti Efrat, Geresh Shimona, Vago Razi
Abstract excerpt
Adipogenic and osteogenic cells share part of the early differentiation cascade of mesenchymal stem cells (MSCs). The choice of a mesenchymal precursor cell to differentiate into a particular cell type is dictated by many spatial and temporal cues, including growth factors, neighboring mature cells, and the extracellular matrix (ECM), which plays an important role in bone formation. Whether adipocytes that have...
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