Article
Validation of a standardized extraction method for formalin-fixed paraffin-embedded tissue samples.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2016
Lagheden Camilla, Eklund Carina, Kleppe Sara Nordqvist, Unger Elizabeth R, Dillner Joakim, Sundström Karin
Abstract excerpt
BACKGROUND: Formalin-fixed paraffin-embedded (FFPE) samples can be DNA-extracted and used for human papillomavirus (HPV) genotyping. The xylene-based gold standard for extracting FFPE samples is laborious, suboptimal and involves health hazards for the personnel involved. OBJECTIVES: To compare extraction with the standard xylene method to a xylene-free method used in an HPV LabNet Global Reference Laboratory at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.