Article
Infectious titres of human papillomaviruses (HPVs) in patient lesions, methodological considerations in evaluating HPV infectivity and implications for the efficacy of high-level disinfectants.
EBioMedicine - 1 Jan 2021
Ozbun Michelle A, Bondu Virginie, Patterson Nicole A, Sterk Rosa T, Waxman Alan G, Bennett Erica C, McKee Rohini, Sharma Ankur, Yarwood Jeremy, Rogers Marc, Eichenbaum Gary
Abstract excerpt
BACKGROUND: Recent publications from a single research group have suggested that aldehyde-based high-level disinfectants (HLDs), such as ortho-phthalaldehyde (OPA), are not effective at inactivating HPVs and that therefore, patients may be at risk of HPV infection from medical devices. These results could have significant public health consequences and therefore necessitated evaluation of their reproducibility...
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