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Article

Changes in variation at the MHC class II DQA locus during the final demise of the woolly mammoth.

Scientific reports - 4 May 2016

Pečnerová Patrícia, Díez-Del-Molino David, Vartanyan Sergey, Dalén Love

Abstract excerpt

According to the nearly-neutral theory of evolution, the relative strengths of selection and drift shift in favour of drift at small population sizes. Numerous studies have analysed the effect of bottlenecks and small population sizes on genetic diversity in the MHC, which plays a central role in pathogen recognition and immune defense and is thus considered a model example for the study of adaptive evolution....

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Identifiers

PMID: 27143688
DOI: 10.1038/srep25274
PMCID: PMC4855147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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