Article
Abundance of LRP12 C-rs9694676 allelic promoter variant in epilepsy-associated gangliogliomas.
Life sciences - 15 Jun 2016
Robens Barbara K, Gembé Eva, Fassunke Jana, Becker Albert J, Schoch Susanne, Grote Alexander
Abstract excerpt
AIMS: Chronic epilepsy associated gangliogliomas (GGs) represent tumors composed of irregularly distributed, often dysmorphic, neurons and neoplastic astroglia. The pathogenesis of GGs is largely unknown. Low-density lipoprotein receptor-related protein 12 (LRP12) is critical for brain development and involved in tumorigenesis of non-cerebral neoplasms. MAIN METHODS: Here, we have examined a potential role of...
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