Analysis of LGI1 promoter sequence, PDYN and GABBR1 polymorphisms in sporadic and familial lateral temporal lobe epilepsy.

doi:10.1016/j.neulet.2008.02.045

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Article

Analysis of LGI1 promoter sequence, PDYN and GABBR1 polymorphisms in sporadic and familial lateral temporal lobe epilepsy.

Neuroscience letters - 2 May 2008

Bovo Giorgia, Diani Erica, Bisulli Francesca, Di Bonaventura Carlo, Striano Pasquale, Gambardella Antonio, Ferlazzo Edoardo, Egeo Gabriella, Mecarelli Oriano, Elia Maurizio, Bianchi Amedeo, Bortoluzzi Stefania, Vettori Andrea, Aguglia Umberto, Binelli Simona, De Falco Arturo, Coppola Giangennaro, Gobbi Giuseppe, Sofia Vito, Striano Salvatore, Tinuper Paolo, Giallonardo Anna T, Michelucci Roberto, Nobile Carlo

Abstract excerpt

Autosomal dominant lateral temporal epilepsy (ADTLE) is a genetically transmitted epileptic syndrome characterized by focal seizures with predominant auditory symptoms likely originating from the lateral region of the temporal lobe. Mutations in coding region or exon splice sites of the leucine-rich, glioma-inactivated 1 (LGI1) gene account for about 50% of ADLTE families. De novo LGI1 mutations of the same kind...

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Identifiers

PMID: 18355961
DOI: 10.1016/j.neulet.2008.02.045

Genes

LGI1
GABBR1
PDYN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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