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Article

Race-specific genetic risk score is more accurate than nonrace-specific genetic risk score for predicting prostate cancer and high-grade diseases.

Asian journal of andrology - 1 Jan 2000

Na Rong, Ye Dingwei, Qi Jun, Liu Fang, Lin Xiaoling, Helfand Brian T, Brendler Charles B, Conran Carly, Gong Jian, Wu Yishuo, Gao Xu, Chen Yaqing, Zheng S Lilly, Mo Zengnan, Ding Qiang, Sun Yinghao, Xu Jianfeng

Abstract excerpt

Genetic risk score (GRS) based on disease risk-associated single nucleotide polymorphisms (SNPs) is an informative tool that can be used to provide inherited information for specific diseases in addition to family history. However, it is still unknown whether only SNPs that are implicated in a specific racial group should be used when calculating GRSs. The objective of this study is to compare the performance of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27140652
DOI: 10.4103/1008-682X.179857
PMCID: PMC4955174

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