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Article

Mutation in ADORA1 identified as likely cause of early-onset parkinsonism and cognitive dysfunction.

Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2016

Jaberi Elham, Rohani Mohammad, Shahidi Gholam Ali, Nafissi Shahriar, Arefian Ehsan, Soleimani Masoud, Moghadam Abolfazl, Arzenani Mohsen Karimi, Keramatian Farid, Klotzle Brandy, Fan Jian-Bing, Turk Casey, Steemers Frank, Elahi Elahe

Abstract excerpt

BACKGROUND: We aimed to identify the genetic cause of neurological disease in an Iranian family whose manifestations include symptoms of parkinsonism and cognitive dysfunction. METHODS: Clinical data on the patients were gathered by interviews with parents, neurological examinations, and laboratory tests. Genetic analysis was performed by genome-wide single-nucleotide polymorphism homozygosity mapping and exome...

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Source

Identifiers

PMID: 27134041
DOI: 10.1002/mds.26627

Genes

ADORA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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