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Article

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis.

Human genetics - 1 Jul 2016

Guan Jinting, Yang Ence, Yang Jizhou, Zeng Yong, Ji Guoli, Cai James J

Abstract excerpt

Autism spectrum disorder (ASD) is characterized by substantial phenotypic and genetic heterogeneity, which greatly complicates the identification of genetic factors that contribute to the disease. Study designs have mainly focused on group differences between cases and controls. The problem is that, by their nature, group difference-based methods (e.g., differential expression analysis) blur or collapse the...

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PMID: 27131873
DOI: 10.1007/s00439-016-1673-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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