Article

Hidden Transcriptome Signature in Autism Spectrum Disorder (ASD) is Attributed to the Interpatient Heterogeneity

2021-01-02

Abstract excerpt

Recent studies of ASD have mostly supported the existence of heterogeneity and genomic variation in ASD which have hindered and restrained development of any effective and targetable treatment for a long time. As numerous studies have shown, both genetic and phenotypic heterogeneity is presented in ASD, however, heterogeneity in genetic level is not fully understood which is the key challenges for the further rese...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8adc3675-fd64-5139-b9c9-ce545889863b
DOI: 10.1101/2020.12.30.424910

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hidden Transcriptome Signature in Autism Spectrum Disorder (ASD) is Attributed to the Interpatient HeterogeneityDOI 10.1101/2020.12.30.424910Read

Decomposing the genetic risk of autism spectrum disorder into discrete molecular subtypes underlie clinical heterogeneity based on transcriptome profile.Semantic proximity Read

Genetic neurocognitive profile of autism unveiled with gene transcriptionSemantic proximity Read

DGH-GO: Dissecting the Genetic Heterogeneity of complex diseases using Gene OntologySemantic proximity Read

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosisSemantic proximity Read

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis.Semantic proximity Read

Searching for convergent pathways in autism spectrum disorders: insights from human brain transcriptome studies.Semantic proximity Read

Single cell transcriptomic analysis of autism associated gene expression in human cerebral cortex developmentSemantic proximity Read

Identifying Subgroups of Patients With Autism by Gene Expression Profiles Using Machine Learning AlgorithmsSemantic proximity Read

A Combined Proteomics and Metabolomics Profiling to Investigate the Genetic Heterogeneity of Autistic ChildrenSemantic proximity Read

Cell type-specific predictive models for prioritizing genes and gene sets associated with autism spectrum disorderSemantic proximity Read

SFARI Genes and where to find them; classification modelling to identify genes associated with Autism Spectrum Disorder from RNA-seq dataSemantic proximity Read

Comorbid Analysis of Genes Associated with Autism Spectrum Disorders Reveals Differential Evolutionary ConstraintsSemantic proximity Read